The GROWTH consortium, funded by the European Commission (2019-2023), is made up to train a new generation of researchers working on new pathological insights, biomarker diagnostics and personalized nutritional interventions for intestinal failure in neonates and preterm infants.
Academic and industry partners, covering various disciplines ranging from fundamental research to clinical paediatrics and analytical chemistry to organoid and gut-on-chip applications, have teamed up in the European Union.
GROWTH aims to set-up a new European platform that trains young scientists in the industry-led exploration of innovative routes to fully exploit the potential of early life nutrition to prevent inflammatory disease. GROWTH coordinates 8 individual research projects.
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GROWTH researcher, Gemma Pitotti, prepared a poster and presented her work at the Digestive Disease Week. Her poster had the title: "Activation and function of epithelial TLR4 and TLR5 in E.coli sepsis in preterms".
Naomi Wieser presented her work at the Digestive Disease Week at the plenary session on Development of the liver, Pancreas and Gastrointestinal Tract. Her presentation title was "Human milk and neonatal gut bacterial derived aryl hidrocarban receptor ligands reduce NFkb and chemokine activation in human fetal organoids".
Several GROWTH fellows are invited to prepare an oral presentation and an abstract for the Digestive Disease Week 2022 (21-24 May 2022). Important and exciting times for them in San Diego.
At the Digestive Disease Week compelling data is presented by Konstantina Zafeiropoulou, PhD student at the Tytgat Institute at Amsterdam UMC and collaborator on GROWTH projects conducted by Hilal Sengul and Lilly Bantavi.
In this review, published by the group of Wouter de Jonge (AMC), the conventional and more recently developed in vitro and ex vivo systems focusing on their applications, advantages, and limitations are summarized.